FREE SHIPPING! On online orders of $74+. Use code: SHIP74 
Access Denied
IMPORTANT! If you’re a store owner, please make sure you have Customer accounts enabled in your Store Admin, as you have customer based locks set up with EasyLockdown app. Enable Customer Accounts
5-MTHF 1 MG
$24.99
$24.99
0% OFF
Description
Supplement Facts
Product Reviews
5-MTHF is an active, tissue-ready form of folate. It's an essential B vitamin that supports methylation. Many individuals don't get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic makeup.
Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects, which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin, melatonin, dopamine, epinephrine, and norepinephrine, supplementation supports healthy mood.
Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner.
It is important for a woman of childbearing age to get enough folic acid – not just those women who are planning to become pregnant.* Because half of pregnancies are unplanned, any woman who could become pregnant should get enough folic acid every day. Folic acid intake is especially important before conception and during early pregnancy, since its biggest need is during the first trimester – when a woman might not even know she is pregnant. Supplementation with the active form of folic acid – 5-MTHF (L-5 Methyltetrahydrofolate)– is always preferable.
Acting with vitamin B12, 5-MTHF functions as a methyl-group donor, thereby facilitating the conversion of the amino acid homocysteine to methionine. An elevated homocysteine level is a risk factor for a number of undesirable health conditions. Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.
Take 1 capsule one to three times daily or as recommended by a health-care practitioner.
Supplement Facts
Serving size: 1 capsule
| Amount per capsule | % DV | |
|---|---|---|
| Folate (1 mg as L-5-Methyltetrahydrofolate†) |
1.7 mg DFE | 425% |
† Daily Value (DV) not established.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Suggested Use: Adults take 1 capsule daily with food.
Storage: Refrigerate for optimal quality.
B
Barbara My doc wants me to take this and methyl B12 because my homocysteine is too high and I have the MTHFR gene mutation. I haven’t taken it long enough to see any difference in homocysteine levels, but I do notice a couple positive things: 1. My hair has stopped falling out by the hands full, 2. The myriad of seborrheic keratosis “barnacles” that I have all over have started to disappear.
Unfortunately, this stuff is like pure speed to my system. I have to take it very early in the morning and now have to take melatonin to sleep. Still experimenting with how much and what kind. Could be worse I guess !
Practitioner Brands
Physicians and healthcare practitioners trust these brands due to extensive clinical research and the exceptional quality, purity, and effectiveness of their ingredients.
Just 3 Simple Steps Towards
A Healthier You
Easy ordering at your fingertips
Order today
Add the products you need from our online store and proceed to checkout.
We Ship With in 24 Hours
We ship within 24 hours excluding weekends and holidays. Tracking information will be sent to you via email.
Be Healthy & Happy
Optimize your health with our high-quality nutritional products and expert guidance.
A DIFFERENT KIND OF PHARMACY WHERE YOU'RE NEVER JUST A NUMBER
Trusted Reputation, Expertise, and Personalized Support
KNOWLEDGEABLE STAFF
- Expert pharmacists, nutritionists, herbalists, clinicians, and more.
- Personalized guidance tailored to each customer's unique needs.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Our integrative pharmacy offers comprehensive information on nutritional supplements, as well as drug-nutrient and drug-herb interactions and nutrient depletions — information that is not typically provided by most pharmacies.
CUSTOM COMPOUNDING SOLUTIONS
- Unique combinations of drugs and nutrients personalized to you.
- Accurate and customized dosages for optimal effectiveness.
- Many forms to choose from, including capsules, liquids, creams, and more.
For over 30 years, Village Green Apothecary's compounding pharmacy has excelled in custom formulations of nutrients (vitamins, minerals, amino acids), herbs, and prescription drugs. Our specially trained pharmacists can work with you to meet your unique needs.
IN-DEPTH NUTRITION & WELLNESS CONSULTATIONS
- One-on-one consultations, in person or via phone call.
- Tailored diet, supplement, and lifestyle recommendations to meet your health goals.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Working with a nutrition expert can help you address your health concerns and support you in achieving your health goals. Utilizing specialty lab testing, such as nutrient analysis, adrenal and hormone tests, and food sensitivity panels, can provide further important insights into your health.
Supporting Thousands On Their Wellness Path Every Day
Let customers speak for us
from 937 reviews5 Stars
The staff is incredibly helpful and always willing to special order supplements. I also find their supplements to be high quality.
I love shopping here for my supplements. The staff are so helpful
Papaya Complete
This is our first time taking this brand. So far, so good. We think it helps. Just ordered more so that’s a good sign. Thank you.
CARA 100% Dermatological Cotton Gloves, Large
Migraine Prevention
This supplement is part of a regimen I started about 6 months ago. It is working and my migraines have decreased by 75%
Senna
The tea works thanks to the Senna in it. Doesn’t taste bad either
GABA Max
I have been using GABA Max for about 6 years. It helps calm me in stressful days. It also helps me sleep on nights when I wake up and can’t go back to sleep. I always want to keep this in my cabinet for such occasions
Love this store
I have been coming to this store before it was Village Green. It’s always been an amazing experience. I recommend it to everyone I know.
Wonderful
They are So helpful with any health question you have. I have seen a major difference in my health and overall inflammation in my body from the herbs they have recommended.
Amazing, I use it as a winter face cream
Great product! I use it on my face as a night moisturizer when it's cold outside. It absorbs really well and provides a nice understated glow. I strongly suggest using a small scoop to get it out of the tin, so you don't contaminate it. A little goes a long way. Also, I have a super sensitive skin that breaks out from everything and I don't break out from this. Will definitely buy again.
Great staff and quality products.
I have been coming here for years. They have always taken care of me each time with patience. A staple in the community and my life. Thank you.
I love this place!
You can find almost any kind of supplement here. And Brian is an absolute treasure; he's super-knowledgeable, and his suggestions and guidance have been extremely valuable!
Samento, Immune/Microbial Support
The Mane Thing
Started taking after neck fusion surgery to relieve pressure on nerves. Recovery had stalled and function was reduced in my right arm due to nerve damage. After starting Lion's Mane at Village Green's suggestion began to regain function with continued improvement over the next months. Also reduced frequency and severity of nerve 'blasts' in my leg from unrelated issue -- believe me, I take it every day!
Organic Original Bitters
My favorite bitters - will purchase again!
FREQUENTLY ASKED QUESTIONS
What makes Village Green different?
Unlike traditional pharmacies and large retail supplement stores, we prioritize personalized care and attention. We take the time to understand your unique health conditions and needs, offering tailored solutions and a wide range of traditional and alternative wellness resources.
As a leading integrative pharmacy, we have over 10,000 nutritional supplements
and natural body care products, books, and more. We offer in-depth nutritional consultations, lab testing, and compounding. Our pharmacists and nutrition experts are well-versed in the nutritional depletions caused by certain medications and can offer insights into potential interactions between drugs, nutrients, and herbs.
Why should I choose Pathway supplements?
Our exclusive Pathway line has been developed by a team of expert pharmacists, nutritionists, and clinicians, combining extensive knowledge of healthy living with high-quality ingredients. We offer excellent value and our frequent sales provide our customers with terrific cost savings.
Where are you located?
Our "brick and mortar" location is in Bethesda, MD, conveniently serving the DC Metro area, including Rockville, Kensington, Silver Spring, Takoma Park, Potomac, Chevy Chase, Gaithersburg, Washington DC, and Northern Virginia. Additionally, our website serves customers nationwide.
What is your return policy?
You have a 100-day window to return Pathway supplements for a full refund.
Other nutritional supplements: Unopened nutritional supplements are eligible for a full refund within 30 days or a store credit within 100 days. Opened nutritional supplements can be returned for a store credit within 100 days.
You may return personal care products within 30 days, provided they are still sealed and in resaleable condition.
Please note that the following items cannot be returned: refrigerated items, books, over-the-counter (OTC) items, prescriptions and compounds, special order products, and braces/personal wear.
If you have any further questions or need assistance, our dedicated customer support team is ready to help. Feel free to reach out to us or refer to our website for more detailed information on the return process.
MORE SUPPLEMENTS FOR A HEALTHIER YOU
sale
PATHWAY
35 Billion Probiotic
2 reviews
$68.79
$85.99
Ultra High Potency Probiotic for Extra Intestinal Support Beneficial bacteria are critical to a healthy digestive and immune system. This high potency probiotic blend is recommended when advanced support is needed due to antibiotic use, travel, or digestive concerns. Pathway 35 Billion Probiotic features 8 strains of beneficial bacteria that are stabilized so that no refrigeration is necessary. In addition, the bacteria are designed to survive stomach acids so that they can work effectively in your intestine. Suggested Use: 1 capsule during meals
sale
PATHWAY
20 Billion Probiotic
No reviews
$51.19
$63.99
GI & Immune HealthPathway 20 Billion Probiotic is a high potency formula that features 9 strains of clinically researched probiotic strains. Through patented processes, these strains have been designed to survive stomach acid and are stabilized so that they do not require refrigeration. Pathway 20 Billion Probiotic also includes 2 sources of prebiotic fiber, which has been shown to increase the growth of beneficial flora while decreasing pathogenic bacteria. Suggested Use: 1 capsule daily with meals
sale
Klaire Labs - SFI Health
Active B12-Folate
No reviews
$25.99
$25.99
Supports red blood cell function, energy metabolism, and neurological health
Benefits and Features
High-potency, bioavailable, fast-dissolving tablets
Promotes healthy mood
Supports brain, vascular, and nervous system function
Detail Overview
Methylfolate (active folate) and methylcobalamin (Vitamin B12) support vascular, mood, brain, and nervous system function in a form that's easy for your body to digest, absorb, and use.
sale
THORNE RESEARCH
5-Hydroxytryptophan
1 review
$39.00
$39.00
5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep, mood, aggression, appetite, temperature, sexual behavior, and pain sensation.*
Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because, unlike L-tryptophan, 5-HTP cannot be shunted into niacin or protein production.* Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.
5-HTP is well absorbed when taken orally, with about 70 percent ending up in the bloodstream.*
Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore, it may be taken with meals without reducing its effectiveness.* 5-HTP easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin.*
5-HTP has been shown to have a beneficial impact on mood, discomfort associated with fatigue, sleep, and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*
To further facilitate serotonin production, Thorne Research's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.* 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
Two Capsules Contain: Vitamin B6 (as Pyridoxal 5'-Phosphate) 6.8 mg. 5-Hydroxytryptophan 100 mg.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
sale
XYMOGEN
ActivNutrients without Iron
No reviews
$48.99
$48.99
ActivNutrients without Iron features a premium, multivitamin/mineral blend of high-quality vitamin and mineral forms selected for optimum utilization. The comprehensive nutrient profile is delivered in a vegetarian capsule and supports foundational wellness; provides antioxidant activity with vitamins C and E, selenium, and beta-carotene; and supports detoxification.
Product Highlights:
Foundational Nutrition
Basic Formula for Wellness
Supports Antioxidant Activity
Supports Detoxification
Supports Health in Individuals with Inadequate Nutrient Intake
Supports Energy Production and Stress Response
Directions & Usage:
Take two capsules twice daily, or as directed by your healthcare professional.
Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.
Storage:
Keep closed in a cool, dry place out of reach of children.
sale
THORNE RESEARCH
Amino Complex Berry
No reviews
$52.00
$52.00
Promotes lean muscle mass and strength, and enhances energy production
Amino Complex is a comprehensive blend of essential amino acids. It is best taken after a workout to help trigger the recovery process. NSF Certified for Sport®
Amino Complex is NSF Certified for Sport®. It supports sports-related, fitness-related, and training-related activities, and it promotes the increase of muscle mass for someone needing that benefit, including the elderly. Amino acid supplementation can decrease fat synthesis, improve redox status, and promote energy production via activation of NRF-2 and PGC-1alpha. Amino acids also promote mitochondrial biogenesis – the body's internal production of energy. The comprehensive blend of essential amino acids in Amino Complex is high in branched-chain amino acids, a group of amino acids that have been validated through numerous clinical trials to promote the growth of lean muscle mass and enhance muscle strength. This active ingredient formulation in Amino Complex is backed by more than 25 years of scientific and clinical research. Amino Complex comes in two flavors, lemon and berry, and is lightly sweetened. It mixes easily with warm or cold liquids, has no artificial sweeteners, and contains flavors only derived from natural sources.
Because an athlete needs to know that his or her supplements are trustworthy and compliant, every batch of an NSF Certified for Sport® product is tested for compliance with label claims and to ensure the absence of more than 200 substances banned by many major athletic organizations, including stimulants, narcotics, steroids, diuretics, beta-2 agonists, and masking agents.
Mix 1 scoop with 6 ounces of water one to two times daily or as recommended by your health professional.
Servings per container: 30
sale
NORDIC NATURALS
ProOmega in Fish Gelatin
No reviews
$27.84
$32.75
High-intensity support for cardiovascular, neurological, eye, joint, and immune health in fish gelatin soft gels
ProOmega in Fish Gelatin provides high-intensity, omega-3 fatty acid support for optimal cardiovascular, neurological, eye, joint, and immune functioning.
Healthy Benefits:
Fish gelatin soft gels make this ProOmega ideal for pescatarians
Optimizes cognitive, visual, and neurological health by facilitating cellular flexibility and communication
Supports cardiovascular function by maintaining healthy triglyceride and blood pressure levels
Suggested Use:
Two fish soft gels daily, with food, or as directed by your health care professional or pharmacist.
For intense support, take two soft gels with food twice daily.
sale
PURE ENCAPSULATION
A.I. Enzymes 120's
No reviews
$77.00
$77.00
Balanced plant enzyme formula for muscle and joint comfort
Made with ingredients derived from pineapple and papaya that have been clinically proven to support digestion when taken with food
Made with hypoallergenic, vegan ingredients
A.I. Enzymes provides purified, high potency support for digestive function and to help maintain healthy muscles and joints. When taken with meals, this plant enzyme blend promotes the breakdown of protein, carbohydrates and fat for optimal digestion. The plant enzymes help replace naturally-occurring enzymes that are destroyed in highly processed and cooked foods.A.I. Enzymes provides a superior combination of natural plant enzymes precisely balanced for broad spectrum support of digestive function and to help maintain healthy joints and muscles. This formula contains enhanced levels of protease, amylase and lipase sourced from Aspergillus oryzae and Aspergillus niger. Bromelain (from pineapple) and papain (from papaya), provided in their highest potencies, add to the protease profile of this formula. Taken between meals, A.I. Enzymes promotes healthy levels of kinins and fibrin, thereby helping to maintain normal muscle and joint function. Taken with meals, the plant enzymes help replace naturally-occurring enzymes that are destroyed in highly processed and cooked foods. This plant enzyme blend promotes the breakdown of protein, carbohydrates and fat.
WHY WAIT?
GRAB IT NOW!
5-MTHF is an active, tissue-ready form of folate. It's an essential B vitamin that supports methylation. Many individuals don't get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic makeup. Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the thre...
Invalid password
Enter
Stay Connected
Village Green Apothecary
5415 W Cedar Ln
Bethesda, Maryland, 20814
(301) 530-0800
Toll Free: (800) 869-9159
The information provided on this site is not intended to be a substitute for advice or treatment from a qualified physician, nor is it intended to diagnose or treat a health problem or disease. Consult your physician prior to starting any new health program or if you any questions regarding a medical condition.
© 2025 Village Green Apothecary - All Rights Reserved.
