DAO Enzyme
Bloating after meals. Headaches after wine. Flushing after leftovers. Sound familiar?
DAO Enzyme supports healthy histamine breakdown so you can enjoy the foods you love with comfort and confidence.
How to Use It:
- With meals: Take 1 capsule before eating or drinking anything high in histamine such as aged cheeses, wine, fermented foods, cured meats, leftovers, citrus, or overly ripe fruit. This is the most common use and where most people notice the most support.
- On an empty stomach: This is the one most people miss and is actually quite a genius trick. Your gut bacteria and your gut's immune system also produce histamine. If you have dysbiosis, SIBO, or an overactive gut immune response, try taking 1 capsule on an empty stomach. If you feel better within 30 minutes, that tells you your microbiome or gut immune system is producing excess histamine. Continue using it this way as needed.
- For children: Ages 4 and up. Open the capsule and sprinkle on a bite of applesauce if they can't swallow it.
- During pregnancy: With your healthcare professional's approval. Your placenta produces massive amounts of DAO but not until the 2nd trimester, which is exactly when most morning sickness eases. Supporting healthy histamine levels during the 1st trimester may support comfort.
- While breastfeeding: Histamine from your gut absorbs into breast milk. Infant colic is associated with higher histamine levels in breast milk. Supporting your own histamine balance may support comfortable feeding for your baby.
When to Reduce or Stop:
- DAO Enzyme is what I call a palliative supplement. It provides the enzyme your body needs right now, but it doesn't fix the underlying reason your DAO may be low. The goal is to heal your gut lining, rebalance your microbiome, and calm your immune system so your body's own DAO enzyme works well on its own.
- As you make progress in those areas, you'll naturally need less DAO Enzyme. Some people go from taking it at every meal to only when they eat out or travel. Others find they eventually only need it during high-histamine seasons or stressful periods. Let your body guide you.
- If your stools become harder to pass, that's a sign you may be taking too much. High histamine in the gut is associated with loose stools so when you lower it effectively, things can firm up more than expected. Simply reduce your dose to mealtimes only, or take a break. If things normalize, adjust accordingly.
Suggested Use:
- As needed, anytime, take 1 capsule before eating or drinking.
- Alternatively, as needed, take 1 capsule away from food or drink if wanting to support uterine comfort during the menstrual cycle, occasional nausea from pregnancy or healthy histamine levels in your digestive system.
- Capsules may be opened and sprinkled on a bite of food.
- Use as directed by your healthcare professional.
Suitable for: Bariatric, methyl-sensitive, pregnancy, breastfeeding, ages 4 and up
NOT Suitable for: Vegetarians, vegans, infants
Delivery Method: Capsules
Age Suitability: Adults, age 4 and up
How to Store: Keep closed in a cool, dry place out of reach by children.
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Capsule Servings Per Container: 90 | ||
| Amount Per Serving | Amount | % DV |
| DAOgest® porcine kidney extract (Diamine Oxidase Activity 30,000 HDU) | 4.2 mg | * |
| * Daily Value (DV) not established. | ||
Just 3 Simple Steps Towards
A Healthier You
Easy ordering at your fingertips

Order today
Add the products you need from our online store and proceed to checkout.

We Ship With in 24 Hours
We ship within 24 hours excluding weekends and holidays. Tracking information will be sent to you via email.

Be Healthy & Happy
Optimize your health with our high-quality nutritional products and expert guidance.
A DIFFERENT KIND OF PHARMACY WHERE YOU'RE NEVER JUST A NUMBER
Trusted Reputation, Expertise, and Personalized Support
KNOWLEDGEABLE STAFF
- Expert pharmacists, nutritionists, herbalists, clinicians, and more.
- Personalized guidance tailored to each customer's unique needs.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Our integrative pharmacy offers comprehensive information on nutritional supplements, as well as drug-nutrient and drug-herb interactions and nutrient depletions — information that is not typically provided by most pharmacies.
CUSTOM COMPOUNDING SOLUTIONS
- Unique combinations of drugs and nutrients personalized to you.
- Accurate and customized dosages for optimal effectiveness.
- Many forms to choose from, including capsules, liquids, creams, and more.
For over 30 years, Village Green Apothecary's compounding pharmacy has excelled in custom formulations of nutrients (vitamins, minerals, amino acids), herbs, and prescription drugs. Our specially trained pharmacists can work with you to meet your unique needs.
IN-DEPTH NUTRITION & WELLNESS CONSULTATIONS
- One-on-one consultations, in person or via phone call.
- Tailored diet, supplement, and lifestyle recommendations to meet your health goals.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Working with a nutrition expert can help you address your health concerns and support you in achieving your health goals. Utilizing specialty lab testing, such as nutrient analysis, adrenal and hormone tests, and food sensitivity panels, can provide further important insights into your health.
Supporting Thousands On Their Wellness Path Every Day
Let customers speak for us
from 1039 reviews
Definitely helps
We received our order in a timely manner. Thank you.
I have been getting supplements from Village Green for years and have never had a problem. They are great to deal with and will always answer your questions. Shipping arrives on time and I feel that I can trust their products.
Causticum (6c)
Multi Collagen Protein - Chocolate
Hydrate taste great.
Love this product. I use it for my German Shepherds arthritis! Apparently the product works too good because it's always close to being sold out. I'm hoping it can stay in stock. Will continue to buy!!
Fermented Cod Liver Oil – Capsule – MSC certified
Dr Wilsons Adrenal C Formula
I have been using metagenics for many years and this is the best calcium supplement. It has helped me maintain bone strength and health.
and great product for eye support
I love this product,however,I will soon need more and you don't have any and that does not make me very happy.
I STARTED USING B1 ABOUT 5 YEARS AGO BECAUSE THE SLEEVES IN MY MIDDLE FINGERS WAS FREEZING UP AND IT WAS HARD TO OPEN AND CLOSE THE FINGER I WAS 2 WEEKS AWAY FROM HAVING A HAND SURG. IN SARASOTA FL CUT THE TENDONS WHEN A FRIEND TOLD ME ABOUT B1 AN HAVE HAD NO TROUBLE SENCE JIM
Ty I will be ordering again
All good
FREQUENTLY ASKED QUESTIONS
What makes Village Green different?
As a leading integrative pharmacy, we have over 10,000 nutritional supplements
Why should I choose Pathway supplements?
Where are you located?
What is your return policy?
MORE SUPPLEMENTS FOR A HEALTHIER YOU


WHY WAIT?
GRAB IT NOW!
Bloating after meals. Headaches after wine. Flushing after leftovers. Sound familiar? DAO Enzyme supports healthy histamine breakdown so you can enjoy the foods you love with comfort and confidence. How to Use It: With meals: Take 1 capsule before eating or drinking anything high in histamine such as aged cheeses, wine, fermented foods, cured meats, leftovers, citrus, or overly ripe fruit. This is the most common use and ...

Village Green Apothecary
5415 W Cedar Ln
Bethesda, Maryland, 20814
(301) 530-0800
Toll Free: (800) 869-9159
The information provided on this site is not intended to be a substitute for advice or treatment from a qualified physician, nor is it intended to diagnose or treat a health problem or disease. Consult your physician prior to starting any new health program or if you any questions regarding a medical condition.
© 2025 Village Green Apothecary - All Rights Reserved.

