Grape Seed Extract (formerly O.P.C.-100)




















The primary constituents of Thorne's grape seed extract are oligomeric proanthocyanidins (OPCs). OPCs have strong free-radical scavenging (antioxidant) ability, resulting in inhibition of oxidative damage and protection of blood vessels and other tissues. OPCs have been shown to protect vascular endothelial cells from oxidative damage and appear to strengthen the resistance of cell membranes to injury and impairment. OPCs also can bind copper and iron, thereby reducing their oxidative effects. Grape Seed Extract contains Leucoselect Phytosome, which have demonstrated in studies to reduce the oxidation of LDL-cholesterol in heavy smokers, and decrease oxidative stress in diabetics and in healthy individuals after a fatty meal.
Evidence suggests OPCs enhance the cross-linkage of collagen in skin and other connective tissues. OPCs have also been shown to decrease capillary permeability, which can be manifest as decreased bruising. For example, clinical studies demonstrate reduced swelling and improved resolution of sports injuries in athletes who were given OPCs prior to a sporting event.
A clinical study of 10 healthy volunteers analyzing the effect of OPC supplementation on biomarkers of oxidative stress found significantly increased levels of the antioxidant alpha-tocopherol in red blood cell membranes.
In a randomized human trial, young healthy volunteers received 300 mg of Leucoselect phytosome daily or a placebo. Antioxidant activity was measured at multiple time-points during days one and five. Within 30 minutes after administration on day one, the antioxidant activity measured by "total radical-trapping antioxidant parameter" (TRAP) was significantly elevated compared to placebo.
ALLERGY WARNING:
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Grape Seed Extract contains grape seed phytosome - a plant extract complexed with phospholipids, which are derived from soy. Phospholipids contain no soy protein. There are no other soy-based ingredients in Grape Seed Extract.
PREGNANCY:
If pregnant, consult your health professional before using this product.
INTERACTIONS:
There are no known adverse interactions or contraindications at publication date.
How to Use:
Take 1 capsule two to three times daily or as recommended by your health professional.
Supplement Facts
Serving size: One Capsule
Amount per capsule | % DV | |
---|---|---|
Grape Seed Phytosome (Vitis vinifera extract / Phospholipid complex) |
100 mg | * |
*Daily Value (DV) not established.
Other ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Suggested Use: Adults take 1 capsule daily with food.
Storage: Store in a cool, dry place.


Just 3 Simple Steps Towards
A Healthier You
Easy ordering at your fingertips

Order today
Add the products you need from our online store and proceed to checkout.

We Ship With in 24 Hours
We ship within 24 hours excluding weekends and holidays. Tracking information will be sent to you via email.

Be Healthy & Happy
Optimize your health with our high-quality nutritional products and expert guidance.

A DIFFERENT KIND OF PHARMACY WHERE YOU'RE NEVER JUST A NUMBER
Trusted Reputation, Expertise, and Personalized Support

KNOWLEDGEABLE STAFF
- Expert pharmacists, nutritionists, herbalists, clinicians, and more.
- Personalized guidance tailored to each customer's unique needs.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Our integrative pharmacy offers comprehensive information on nutritional supplements, as well as drug-nutrient and drug-herb interactions and nutrient depletions — information that is not typically provided by most pharmacies.
CUSTOM COMPOUNDING SOLUTIONS
- Unique combinations of drugs and nutrients personalized to you.
- Accurate and customized dosages for optimal effectiveness.
- Many forms to choose from, including capsules, liquids, creams, and more.
For over 30 years, Village Green Apothecary's compounding pharmacy has excelled in custom formulations of nutrients (vitamins, minerals, amino acids), herbs, and prescription drugs. Our specially trained pharmacists can work with you to meet your unique needs.


IN-DEPTH NUTRITION & WELLNESS CONSULTATIONS
- One-on-one consultations, in person or via phone call.
- Tailored diet, supplement, and lifestyle recommendations to meet your health goals.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Working with a nutrition expert can help you address your health concerns and support you in achieving your health goals. Utilizing specialty lab testing, such as nutrient analysis, adrenal and hormone tests, and food sensitivity panels, can provide further important insights into your health.
Supporting Thousands On Their Wellness Path Every Day
Let customers speak for us
from 852 reviews
I have used these Quick Stop bandages for years they are great. When I got them in the mail a day later my son’s dog scratched my arm real bad. I’m so glad I had them. It took 6 of the bandages to cover the wound. I wish that they had larger ones. I will always keep using them. Thank you so much.

This product is amazing! I take 2 capsules about 45-60 min before shutting off the lights, and I drift into blissful sleep. I have tried so many products to help my sleep, but this is by far the best!

Vitamin D + K2 Liquid

Whenever I have a urinary tract issue, I turn to Uri-Control for relief.

I feel confident that Core Minerals supplies my body with what it needs.

Great product. Great company. Fast shipping.

Biotin

I am prescribed this detox kit from my biotheraputic oncologist. Village Green has the best price around. This kit helps me get through flu season as an elementary school teacher.

This has been a game changer for me I feel much more healthier.

I have now ordered this beet powder several times. I add it to my morning smoothie. It dissolves well, there is no noticeable weird beet taste to it and it makes my smoothie a much more "palatable" looking reddish-pink color (rather than the dull gray-brown it used to be from the protein and other powders mixed in with it). I like that I am getting heart health and other benefits without having to regularly consume beets!

PectaSol-C Professional - Lime Flavored Powder

ProOmega-D Xtra

My usual supplier stopped selling the glass liter bottles, so I was thrilled to find it here. I'm happy with it! I was a little concerned about the packaging since the bubble wrap was loosely packed and it should be tightly wrapped and a tad thicker but it arrived safely :)

Product seems to work fine. Just started using this product.

I love it, wish that the jars were larger.

FREQUENTLY ASKED QUESTIONS
What makes Village Green different?
As a leading integrative pharmacy, we have over 10,000 nutritional supplements
Why should I choose Pathway supplements?
Where are you located?
What is your return policy?


MORE SUPPLEMENTS FOR A HEALTHIER YOU








































WHY WAIT?
GRAB IT NOW!
The primary constituents of Thorne's grape seed extract are oligomeric proanthocyanidins (OPCs). OPCs have strong free-radical scavenging (antioxidant) ability, resulting in inhibition of oxidative damage and protection of blood vessels and other tissues. OPCs have been shown to protect vascular endothelial cells from oxidative damage and appear to strengthen the resistance of cell membranes to injury and impairment. OPCs a...





Village Green Apothecary
5415 W Cedar Ln
Bethesda, Maryland, 20814
(301) 530-0800
Toll Free: (800) 869-9159
The information provided on this site is not intended to be a substitute for advice or treatment from a qualified physician, nor is it intended to diagnose or treat a health problem or disease. Consult your physician prior to starting any new health program or if you any questions regarding a medical condition.
© 2025 Village Green Apothecary - All Rights Reserved.