5-MTHF 5 mg
Support heart health, fetal development, nervous system, and mood with 5-MTHF5-
MTHF is a bioactive, methylated form of folate, an essential B vitamin that supports heart, brain, blood, and bone health and is suitable for individuals with MTFHR gene mutations.
Folate is a key component in the body’s methylation cycle, a series of biochemical reactions that play a beneficial role in multiple body systems. Heart and brain health, cellular energy production, fat metabolism, liver detoxification, and bone health all rely on a healthy methylation cycle.
Benefits of Thorne’s 5-MTHF:
- Nutritional support for individuals who have an MTHFR gene mutation
- Supports production of key neurotransmitters – serotonin, melatonin, dopamine, and epinephrine – natural brain chemicals that play an important role in regulating brain function and mood
- Promotes cardiovascular, brain, and bone health by maintaining a healthy methylation cycle and a normal homocysteine level
- Supports healthy fetal brain and spinal cord development
- Promotes blood and nerve cell health
Features of 5-MTHF:
- Suitable for individuals who have an MTHFR gene mutation
- Active, methylated folate (5-MTHF) means your body gets the highest benefit with the least additional work
- 1 mg 5-MTHF is recommended for support of fetal development during pregnancy
- Easy-to-take, small capsules
ALLERGY WARNING:
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY WARNING:
If pregnant, consult your health professional before using this product.
INTERACTIONS:
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
How to Use:
Take 1 capsule one to two times daily or as recommended by your health professional.

Supplement Facts
Serving size: 1 capsule
| Amount per capsule | % DV | |
|---|---|---|
| Folate (5 mg as L-5-Methyltetrahydrofolate) | 8.3 mg DFE | 2,075% |
† Daily Value (DV) not established.
Other ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide
Suggested Use: Adults take 1 capsule daily with food.
Storage: Store in a cool, dry place.
Just 3 Simple Steps Towards
A Healthier You
Easy ordering at your fingertips

Order today
Add the products you need from our online store and proceed to checkout.

We Ship With in 24 Hours
We ship within 24 hours excluding weekends and holidays. Tracking information will be sent to you via email.

Be Healthy & Happy
Optimize your health with our high-quality nutritional products and expert guidance.
A DIFFERENT KIND OF PHARMACY WHERE YOU'RE NEVER JUST A NUMBER
Trusted Reputation, Expertise, and Personalized Support
KNOWLEDGEABLE STAFF
- Expert pharmacists, nutritionists, herbalists, clinicians, and more.
- Personalized guidance tailored to each customer's unique needs.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Our integrative pharmacy offers comprehensive information on nutritional supplements, as well as drug-nutrient and drug-herb interactions and nutrient depletions — information that is not typically provided by most pharmacies.
CUSTOM COMPOUNDING SOLUTIONS
- Unique combinations of drugs and nutrients personalized to you.
- Accurate and customized dosages for optimal effectiveness.
- Many forms to choose from, including capsules, liquids, creams, and more.
For over 30 years, Village Green Apothecary's compounding pharmacy has excelled in custom formulations of nutrients (vitamins, minerals, amino acids), herbs, and prescription drugs. Our specially trained pharmacists can work with you to meet your unique needs.
IN-DEPTH NUTRITION & WELLNESS CONSULTATIONS
- One-on-one consultations, in person or via phone call.
- Tailored diet, supplement, and lifestyle recommendations to meet your health goals.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Working with a nutrition expert can help you address your health concerns and support you in achieving your health goals. Utilizing specialty lab testing, such as nutrient analysis, adrenal and hormone tests, and food sensitivity panels, can provide further important insights into your health.
Supporting Thousands On Their Wellness Path Every Day
Let customers speak for us
from 880 reviews
Shark Cartilage 750mg
Turmeric Extract
Fermented Cod Liver Oil and Concentrated Butter Oil Blend – Gel – MSC certified
I have been taking multi - two for several years. It has helped my overall health. I had trouble standing on my feet with pain and my daughter asked me to try them and the first three days I saw little improvement but on the fourth or fifth day I got up one morning feeling better and no pain.
Curaphen Extra Strength
I THINK THAT THE BEST WAY TO SHOW MY APPRECIATION FOF THE EXCELLENT SERVICE AND PRODUCTS WE CAN GET THERE, IS TO SAY THAT MY COMPANION AND I HAD BEEN THE APOTHECARY CLIENTS FOR SEVERAL YEARSF.
I AM VERY BUSY, NO TIME TO GIVE MY OPINION TO THE MANY PRODUCTS I HAD BEEN BUYING THEREFOR LONG TIME..
AGAIN, I AM VERY HAPPY AND GRATEFUL FOR THE EXCELENT PRODUCTS AND THE MOST IMPORTANT TO ME THE GENEROUS HELP I HAD ALL THE TIME.
Excellent source of protein.
ADVANCED BEAUTY CARE
Iron-Free Formula Vm-75
It serves us well
Calendula Cream
Lights out
Not sure if it’s working yet but everything with shipping was great. And no bad side effects. Have finished almost the bottle
Wonderful natural pain product. Take one every night before going to bed.
Two-Per-Day Multivitamin
FREQUENTLY ASKED QUESTIONS
What makes Village Green different?
As a leading integrative pharmacy, we have over 10,000 nutritional supplements
Why should I choose Pathway supplements?
Where are you located?
What is your return policy?
MORE SUPPLEMENTS FOR A HEALTHIER YOU


WHY WAIT?
GRAB IT NOW!
Support heart health, fetal development, nervous system, and mood with 5-MTHF5- MTHF is a bioactive, methylated form of folate, an essential B vitamin that supports heart, brain, blood, and bone health and is suitable for individuals with MTFHR gene mutations. Folate is a key component in the body’s methylation cycle, a series of biochemical reactions that play a beneficial role in multiple body systems. Heart and brain hea...

Village Green Apothecary
5415 W Cedar Ln
Bethesda, Maryland, 20814
(301) 530-0800
Toll Free: (800) 869-9159
The information provided on this site is not intended to be a substitute for advice or treatment from a qualified physician, nor is it intended to diagnose or treat a health problem or disease. Consult your physician prior to starting any new health program or if you any questions regarding a medical condition.
© 2025 Village Green Apothecary - All Rights Reserved.

