TMG 500 MG
Encourages healthy homocysteine levels
Our innovative formula helps support and maintain already-healthy homocysteine levels to support cardiovascular health.
What Is TMG?
Trimethylglycine (TMG) has been linked to heart health by supporting already-healthy homocysteine levels to promote healthy cardiovascular function. By having a positive impact on your homocysteine levels, TMG helps you stay healthy by supporting multiple systems throughout your body.
TMG (also called glycine betaine) has been associated with beneficial effects on liver function and cardiovascular health.
TMG Benefits:
- Promotes healthy homocysteine levels already within normal range
- Helps inhibit inflammatory factors to encourage cardiovascular health
- Supports already-healthy blood pressure levels
- Encourages whole-body health
- Helps maintain healthy mitochondrial function
Trimethylglycine (TMG) is also called glycine betaine, but the name trimethylglycine signifies that it has three methyl groups attached to each molecule of glycine. Wheat bran is the main dietary source of TMG, with smaller amounts available in other cereal grains. TMG can also be made in the body from choline, an essential nutrient found in eggs, soybeans and many other foods.
TMG was found to be beneficial to heart health in the 1950s. Like some of the B vitamins (B6, B12 and folate), TMG is a methyl donor, providing extra methyl groups to hasten the conversion of homocysteine back to methionine. When a TMG methyl group is donated to a molecule of homocysteine, it converts it to the non-toxic amino acid, methionine.
The role of TMG in healthy homocysteine metabolism is even more important when B vitamin levels are low. Some evidence suggests TMG may be more efficient at regulating homocysteine levels than folate. Research showing TMG's ability to promote healthy levels of homocysteine already within normal range, alone or in conjunction with other nutrients, confirms its status as an important nutrient for cardiovascular and overall health.
TMG has been associated with healthy blood pressure and mitochondrial function, and has been found to be linked to cardiovascular health. TMG has also been found to promote healthy liver function. Studies show TMG can support a healthy inflammatory response by inhibiting expression of NFkappaB, TNF-alpha, and other inflammatory proteins, which may partially explain its positive impacts. Because intestinal microbes can make various by-products from TMG, the health of the gut microbiome influences the effects of TMG in the body.
Dosage and Use:
- Take two (2) capsules in the morning, or as recommended by a healthcare practitioner.
- TMG should be taken with co-factors B6, B12, and folic acid.
Warnings:
- KEEP OUT OF REACH OF CHILDREN.
- DO NOT EXCEED RECOMMENDED DOSE.
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
| Supplement Facts | ||
|---|---|---|
| Serving Size: 2 Liquid Vegetarian Capsules Servings Per Container: 30 | ||
| Amount Per Serving | Amount | %DV |
| Trimethylglycine (TMG) (as Betaine Anhydrous) | 1,000 mg | ** |
** Daily Value (DV) not established.
Other Ingredients: Glycerin, Vegetable Cellulose (Capsule), Purified Water.
Storage: Store tightly closed in a cool, dry place.
Just 3 Simple Steps Towards
A Healthier You
Easy ordering at your fingertips

Order today
Add the products you need from our online store and proceed to checkout.

We Ship With in 24 Hours
We ship within 24 hours excluding weekends and holidays. Tracking information will be sent to you via email.

Be Healthy & Happy
Optimize your health with our high-quality nutritional products and expert guidance.
A DIFFERENT KIND OF PHARMACY WHERE YOU'RE NEVER JUST A NUMBER
Trusted Reputation, Expertise, and Personalized Support
KNOWLEDGEABLE STAFF
- Expert pharmacists, nutritionists, herbalists, clinicians, and more.
- Personalized guidance tailored to each customer's unique needs.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Our integrative pharmacy offers comprehensive information on nutritional supplements, as well as drug-nutrient and drug-herb interactions and nutrient depletions — information that is not typically provided by most pharmacies.
CUSTOM COMPOUNDING SOLUTIONS
- Unique combinations of drugs and nutrients personalized to you.
- Accurate and customized dosages for optimal effectiveness.
- Many forms to choose from, including capsules, liquids, creams, and more.
For over 30 years, Village Green Apothecary's compounding pharmacy has excelled in custom formulations of nutrients (vitamins, minerals, amino acids), herbs, and prescription drugs. Our specially trained pharmacists can work with you to meet your unique needs.
IN-DEPTH NUTRITION & WELLNESS CONSULTATIONS
- One-on-one consultations, in person or via phone call.
- Tailored diet, supplement, and lifestyle recommendations to meet your health goals.
- In-depth knowledge of drug, nutrient, herb interactions and depletions
Working with a nutrition expert can help you address your health concerns and support you in achieving your health goals. Utilizing specialty lab testing, such as nutrient analysis, adrenal and hormone tests, and food sensitivity panels, can provide further important insights into your health.
Supporting Thousands On Their Wellness Path Every Day
Let customers speak for us
from 1089 reviews
Great product and price
Great website, excellent products, fast shipping, competitive price points, great customer service and communication and I absolutely love the marine collagen I received. One of the best I’ve ever taken. I will definitely be ordering from you again! Thank you!
Natrum sulphuricum (30c)
Great decaf medium roast coffee. Wonderful
Everyone is knowledgeable and patient. Also, they have a variety of options and products.
Beef Gelatin Unflavored
Very effective when I combine it with slow release melatonin at night for sleep and stress. This was recommended to me by my functional medicine doctor. The allergy free type is good for people with food sensitivities.
Organic Bacopa really does help with my memory. I can tell the difference if I forget to take it!
This product works for me. Was hounded by my dr to start statins because she thought my numbers were dangerously high. I said absolutely not and added Cholesterice. Over this past year my ‘bad’ number is down 50 points and is staying down. Awesome product which really helped me.
Very glad I found Beberine to give me an assist with pre-diabetes and heart disease. Seems to be working really well.
40,000 volts
Red Yeast Rice
I like the taste not too sweet it is just right.
This is the only thing OTC that actually puts me to sleep! Please don't ever stop making it or carrying it!
Have used for several y
FREQUENTLY ASKED QUESTIONS
What makes Village Green different?
As a leading integrative pharmacy, we have over 10,000 nutritional supplements
Why should I choose Pathway supplements?
Where are you located?
What is your return policy?
MORE SUPPLEMENTS FOR A HEALTHIER YOU


WHY WAIT?
GRAB IT NOW!
Encourages healthy homocysteine levels Our innovative formula helps support and maintain already-healthy homocysteine levels to support cardiovascular health. What Is TMG? Trimethylglycine (TMG) has been linked to heart health by supporting already-healthy homocysteine levels to promote healthy cardiovascular function. By having a positive impact on your homocysteine levels, TMG helps you stay healthy by supporting multiple...

Village Green Apothecary
5415 W Cedar Ln
Bethesda, Maryland, 20814
(301) 530-0800
Toll Free: (800) 869-9159
The information provided on this site is not intended to be a substitute for advice or treatment from a qualified physician, nor is it intended to diagnose or treat a health problem or disease. Consult your physician prior to starting any new health program or if you any questions regarding a medical condition.
© 2025 Village Green Apothecary - All Rights Reserved.

